Drujba-Konserv.com Drujba-Konserv.com
Bulgarian Cannery
 
 //               
    ,     ,     

Posted by Lenora on 18.12.2016 17:31:02: sovaldi genotype 1b
1, 2, 3 ... 58, 59, 60  
 
         Drujba-Konserv.com -> General Forum
::  
аильь



: 08 2015
: 7815

: 18, 2016 1:31 pm    : Posted by Lenora on 18.12.2016 17:31:02: sovaldi genotype 1b

We deliver you hope and ability to escape of hepatitis C and leave this life experience behind you.

*
Post subject: Re: sofosbuvir and simeprevir combination
1. Gilead Sciences, Inc. Sovaldi (sofosbuvir) tablets prescribing information. Foster City, CA 2015 Mar.
http://steptoperfection.ru/index.php/en/forum/razdel-predlozhenij/7563-posted-by-beeler-on-18-12-2016-16-53-06-sovaldi-400-mg-price-in-india
Sofosbuvir and Velpatasvir Dosage
2 Alejandro Pérez-Pitarch. Beatriz Guglieri-López. Rafael Ferriols-Lisart. Matilde Merino-Sanjuán. A model-based meta-analysis of sofosbuvir-based treatments in chronic hepatitis C patients, International Journal of Antimicrobial Agents. 2016. 47. 3, 184 CrossRef
Sofosbuvir and Velpatasvir is part of the drug class:
sofosbuvir (Oral route)
http://fishtourism.ru/index.php/kunena/dobro-pozhalovat/1613-posted-by-shafer-reynold-on-18-12-2016-17-12-44-sovaldi-price-in-england
Politico Pro. Report: Look At Overall Impact, Not Pill Price, Of Costly Drugs Debate over the costly new drug treatment for hepatitis C is focused on the $1,000 a pill price tag, but the real issue is the total impact on the health care system and how to systematically deal with it, CVS officials write in a commentary published Sunday. Gilead's Sovaldi "is not really a per-unit cost outlier, but is a 'total cost' outlier because of its high cost combined with a very large population eligible for treatment -; and a beacon for costs of specialty medications generally," CVS Chief Medical Officer Troyen Brennan and Chief Scientific Officer William Shrank argue in the Journal of the American Medical Association. The total cost of treatment -; about $84,000 just for the course of Sovaldi -; is high. When multiplied by the estimated 3 million Americans who have the disease, the potential magnitude comes into focus: $250 billion (Norman, 7/20).
Of all of the drugs that Medicare Part D paid for in 2014, at the top of the list was Sovaldi, the name brand drug that can cure Hepatitis C in 99 percent of cases. Medicare paid more than $3 billion for this drug, compared to the second most prescribed medication, Nexium, which cost Medicare $2.6 billion. There were 7.5 million claims for Nexium, and only 109,543 claims for Sovaldi.
In upcoming CATIE News bulletins we will present data from other phase III trials of sofosbuvir + velpatasvir in participants with the following genotypes and/or issues:
Hepcvir L (Ledipasvir-sofosbuvir (90 mg/400 mg)) is a fixed-dose combination tablet. The recommended dosage is one tablet once daily, with or without food.
Once administered, sofosbuvir is absorbed quickly; a peak concentration in the plasma occurs 0.8 to 1 hour post-dose. 13 Sofosbuvir is 61% to 65% protein-bound and undergoes extra hepatic metabolism. Here it is converted to the primary circulating inactive nucleoside metabolite GS-331007, which is eliminated renally. 14 Consumption of a moderate- or high-fat meal with sofosbuvir increases the area under the curve twofold while only increasing sofosbuvir’s peak concentration (C max ) 1.3-fold. However, these increases in sofosbuvir levels are not considered to be clinically meaningful. 15
http://friendsknock.com/index.php?do=/blog/37014/posted-by-diana-on-18-12-2016-16-45-01-sofosbuvir-e-olysio/
But even without any money from Texas, Sovaldi is making billions of dollars from Medicaid.
Approval of Sovaldi in Japan is based on data from a final-stage clinical trial (Study GS-US-334-0118) conducted in Japan on genotype II hepatitis C-affected patients, including both previously treated and untreated subjects. The patients received an all-oral once-daily therapy combination of Sovaldi and 600-1,000 mg ribavirin for 12 weeks. 96% of the patients showed sustained viremia at the end of the therapy (SVR12). Data was also examined from four other international final-stage studies including FISSION, POSITRON, FUSION, and VALENCE, conducted on hepatitis C patients who have the genotype II viruses.
Gilead Sciences, Inc. (NASDAQ: GILD), hat heute Daten aus zwei Phase-2-Studien und einer Compassionate-Access-Studie (in etwa: anteilnehmender Zugang) bekannt gegeben, bei denen Patienten mit einer fortgeschrittenen Lebererkrankung einmal täglich 400 mg Sovaldi® (Sofosbuvir) zur Behandlung einer chronischen Infektion mit dem Hepatitis-C-Virus (HCV) erhielten. Die Daten werden in dieser Woche bei der 49. Jahresversammlung der Europäischen Gesellschaft zum Studium der Leber (EASL) vorgestellt. Dieser internationale Leberkongress (The International Liver Congress 2014) findet in London statt.
Brand Name. Resof Active Ingredient. Sofosbuvir Form. Tablets Strength. 400mg Manufactured by. Dr. Reddy’s Laboratories Packing. Pack of 28 tablets
Le sofosbuvir peut se prendre avec ou sans aliments.
Sales of Sovaldi were very solid, being the driver in the earnings beat. I remain cautiously optimistic, although I acknowledge the risks related to competing offerings as well as scrutiny about pricing.
Their challenge becomes even more tangled with the FDA’s approval this month of Harvoni, Gilead’s next-generation version of Sovaldi. Unlike Sovaldi, it can cure the most common strain of hepatitis C without interferon and ribavirin. An eight-week regimen costs $63,000, a 12-week supply nearly $95,000. California’s prisons and San Francisco’s jails are still studying whether they can afford it.
http://din-almaty.gov.kz/index.php?option=com_kunena&view=topic&catid=2&id=799&Itemid=719&lang=ru
"The new sofosbuvir therapy offers a much-needed alternative to standard therapy with interferon, which can cause significant side effects for hepatitis C patients," says the study's lead investigator. Dr. Ira Jacobson, chief of the Division of Gastroenterology and Hepatology and Vincent Astor Distinguished Professor of Medicine at Weill Cornell Medical College.
Yoshida et al. ISSN: Concordance of sustained virological response 4, 12, and 24 weeks post-treatment with sofosbuvir-containing regimens for hepatitis C virus. Hepatology 2014; doi: 10.1002/hep.27366. [Impact Factor = 11.19]
O sofosbuvir pertence a uma nova classe de medicamentos denominados de inibidores da polimerase. Pretende-se usar comprimidos de 400mg, uma vez por dia em combinação com os outros remédios.
In this week’s NEJM, Afdhal et al. report the findings of a study involving patients with HCV genotype 1 who have failed treatment with prior interferon-based therapy. Building upon promising phase 2 trial results, they conducted a multicenter phase 3, randomized, open-label study of a fixed dose, once-daily oral combination pill containing sofosbuvir, a nucleotide analogue HCV NS5B polymerase inhibitor approved by the FDA in late 2013, and ledipasvir, a new experimental HCV NS5A protein inhibitor. Eligibility criteria included age 18 years or older, chronic HCV genotype 1 infection, and failure to achieve a sustained virologic response to prior peginterferon and ribavirin treatment, either with or without a protease inhibitor. Four hundred and forty patients, all of whom received the same daily dose of sofosbuvir and ledipasvir, were randomized 1:1:1:1 to one of four treatment groups, including ledipasvir-sofosbuvir for 12 weeks or 24 weeks, either with or without ribavirin. Randomization was stratified by genotype (1a or 1b), prior treatment response (no response versus relapse or virologic breakthrough) and presence or absence of cirrhosis. The primary endpoint was the rate of sustained virologic response at 12 weeks after the end of therapy (SVR 12); SVR 24 was a secondary endpoint.
http://chirkovo.ru/forum/hunting/4986-posted-by-santana-rolland-on-18-12-2016-16-15-09-sofosbuvir-eu-approval.html
Gilead is expected to charge around $80,000 for one treatment course of sofosbuvir in the US. Even if offered at a fraction of this price in developing countries, this drug will be priced out of reach. The patent opposition—a form of citizen review allowed in many countries—offers technical grounds to show a drug does not merit patenting under India's Patents Act. This opposition was filed to ensure that affordable generic versions of sofosbuvir can be produced to help the millions of people infected with chronic hepatitis C in developing countries access the drug.
All things considered, not much has happened yet in terms of actual pricing and reimbursement reform in the US as a result of the 'Sovaldi effect'. However, Sovaldi and its peers will continue to cast a long shadow over the US pricing and reimbursement environment. The immediate outcome has been to focus on discounts – a familiar development in US pharmaceutical procurement. Nonetheless, the outcome may have been vastly different – and the US may have lost its status as a free pricing market for pharmaceuticals – if there were no competitors with similar efficacy poised to enter the market so soon after Sovaldi and their producers were not willing to offer a sharp discount.
Consult the full Canadian Product Monograph for Harvoni for more information on potentially significant drug interactions, including clinical comments.- See more at: http://www.gilead.com/news/press-releases/2014/10/health-canada-issues-notice-of-compliance-for-gileads-harvoni-ledipasvirsofosbuvir-the-first-oncedaily-single-tablet-regimen-for-the-treatment-of-genotype-1-chronic-hepatitis-c#sthash.zq7h1QoN.dpuf :
Play and Listen michael sofia phd the inventor of the groundbreaking hepatitis c drug sovaldi discusses what patients can expect when they begin a therapeutic regimen with What Hepatitis C Patients Need to Know When Starting Sovaldi Regimen Mp3
Sovaldi, developed by U.S.-based Gilead Sciences, will start selling in Japan by the end of the month. The pills treat genotype-2 hepatitis C, which accounts for 20-30% of all cases in the country. In a 12-week clinical trial, 96% of patients that received a combination of Sovaldi and another drug saw the virus disappear.
These are some of the images that we found for within the public domain for your " Sovaldi Launch " keyword. These images will give you an idea of the kind of image(s) to place in your articles. You can always use one of these images but please respect the copyright of the owner, We have provided the source link for you to also credit the image(s) owner.
Greg was a pioneer in what is now referred to as 'Hepatitis C turism'. He was one of the first to take a leap of faith and obtained sofosbuvir pills from India. Many have followed in his footsteps. Seeing this way of getting medicines such as sofosbuvir and ledipasvir is successful, the FixHepC buyers club was organized to help Hepatitis C patients get the medications safely and legally, and without all the strugles Greg had to go through.
http://bezpeka.okht.net/index.php/forum/dobro-pozhalovat/4879-posted-by-sawyer-elwin-on-18-12-2016-17-25-06-sovaldi-interferon-ineligible
As you can see from the table above, Sovaldi and Daklinza cure rate results for genotype 4 were not as strong as those of Harvoni and Zepatier. This is why Sovaldi and Daklinza za very rarely recommended for genotype 4 therapy.
MSF’s response to the China patent office rebuff of Gilead’s application says that”Chinas rejection of a key patent on sofosbuvir goes to show that there are serious questions about whether this drug merits patenting, and sends a strong signal to other countries that are currently reviewing patent applications for the drug. China could prove to be an important supplier for the raw materials as well as the finished product of sofosbuvir. Increased competition from manufacturers in China could help push the price of sofosbuvir down, so that more people can access it. We hope that other countries where Gilead is seeking patents for sofosbuvir are watching closely. Rohit Malpani, Director of Policy & Analysis, MSF Access Campaign.”
Although pleased with the progress on idelalisib, we believe that investor focus will remain on sofosbuvir, which is being developed for treating patients suffering from chronic hepatitis C virus (HCV). The HCV candidate is under priority review in the U.S. (target date: Dec 8, 2013). We note that the U.S. Food and Drug Administration generally reviews those drugs, which offer major advances in treating diseases over existing therapies, on a priority basis. Sofosbuvir is also under review in the EU. Gilead is also seeking approval for the candidate in other countries such as Canada, Switzerland, Turkey and Australia.
TABLET SOVALDI 400MG (SOFOSBUVIR )IMPORT PERMIT No:-ADC/MUM/12B/2014/502 DT 31/12/2014 (LIFE SAVING MEDICINE)
15 Lawitz E, Ghalib R, Rodriguez-Torres M, et al. COSMOS Study: SVR4 results of a once daily regimen of simeprevir (TMC435) plus sofosbuvir (GS-7977) with or without ribavirin in HCV genotype 1 null responders. 20th Conference on Retroviruses and Opportunistic Infections; Atlanta, Georgia, USA; March 3—6, 2013.
But in India, a 28-day supply of a generic version of the drug now costs just $100, according to the company. That’s because Gilead has struck deals with 11 different Indian generic drugmakers to supply affordable versions of its hep C drugs to patients in 101 developing countries. And then there’s Egypt, the nation with the highest incidence of hepatitis C in the world (more than 10% of the population is infected). Gilead slashed the price of branded Sovaldi there by 99%.
http://www.avtourist78.ru/forum/9-%D0%92%D0%B0%D1%88%D0%B8-%D0%B2%D0%BE%D0%BF%D1%80%D0%BE%D1%81%D1%8B/3073-Posted-by-Durkin-on-18122016-163603-sovaldi-genotype-3-cure-rate.html#3073
Gilead has offered other payer-by-payer deals; for instance, its contract with the Veterans Administration covers Sovaldi at $47,000. To win coverage in the U.K.--where cost-effectiveness watchdogs usually wring discounts from drugmakers--it priced Sovaldi at $57,000. In March, the Pennsylvania Medicaid program said it had been paying $70,000 for Sovaldi plus two other drugs; that's most likely ribavirin and interferon rather than newer and more expensive alternatives such as Vertex Pharmaceuticals' now-abandoned Incivek. That would put Sovaldi's portion at about $59,000, give or take a few.
- on a day-to the health- care system. Hurst said new Sovaldi guidelines from California's Medicaid - was only around 50 percent. On Wednesday Gilead reported second quarter sales totaling - emerge about patients being cured. He recently finished a regimen of Sovaldi . which costs $84 - his insurer to treat them from being in the health care system." *** The Centers for Disease Control and - that prevented many of years will save a lot of Express Scripts . As states consider their budgets -
Sovaldi: Médecins du Monde part en guerre contre le coût du remède à l'hépatite C
Sofosbuvir è stato studiato in uno studio clinico in aperto volto a determinare la sicurezza e l’efficacia di 24 settimane di trattamento con sofosbuvir e ribavirina nei riceventi trapianto di fegato con
Express Scripts said Monday that it will no longer cover Sovaldi and Harvoni — two Gilead Sciences drugs that cost more than $80,000 each for a full course of treatment — or Johnson & Johnson's Olysio starting Jan. 1, except under limited circumstances.
High quality anti HCV APIs CAS 1190307-88-0 Sofosbuvir ( PSI-7977 )
DSV = dasabuvir; HCV = hepatitis C virus; LDV = ledipasvir; OBV = ombitasvir; PTV = paritaprevir; r = ritonavir; RBV = ribavirin; SMV = simeprevir; SOF = sofosbuvir
When the FDA approved Harvoni for use in the U.S. it was well known that other products for Hepatitis C were awaiting FDA review and approval. On December 19 the FDA approved Viekira Pak, AbbVie’s oral combination product. On December 22, Express Scripts announced its intent to exclude Harvoni from its formulary and granted Viekira Pak an exclusive position for treating genotype 1 Hepatitis C. Excluding Harvoni from coverage was actually a fulfillment of a commitment made by Express Scripts senior management months before. Express Scripts was a frequent and vocal critic of what they saw as Gilead’s abusive pricing for Sovaldi. Express Scripts promised that if a product became available that was clinically equivalent to a Gilead product and could be obtained at a lower cost, the Gilead product would be removed from the Express Scripts formulary. Negotiations with AbbVie on the net price for Viekira Pak provided Express Scripts the opportunity to live up to its promise and exclude Harvoni from the formulary.
http://webmaster360epta.ru/sovaldi-prix-quebec.html
sovaldi manufacturer Augusta
sovaldi manufacturer HI
Considering the high cost associated with sofosbuvir and other chronic HCV drugs, pharmacists should rethink their formula for determining the drugs’ worth. The drug is excluded from both Express Scripts’ and CVS Caremark’s 2016 formularies.
Missouri also ranks high on Sovaldi spending for each Medicare beneficiary. The federal government spends $77 on the drug for every Missouri Medicare recipient. Only six other states have higher rates. Illinois’ rate is about $54 in spending for each recipient.
For all of the outrage about the $1,000 a day cost for Sovaldi, the new hepatitis C pill marketed by Gilead Sciences, why hasn't anyone been arguing that federal law mandates that it be made available to the public at a reasonable price? If it is not, according to the 1980 revision of US patent law known as the Bayh-Dole Act, the government can use its "march-in" rights and insist that the drug be licensed to other manufacturers that will make the drug more widely available.
Drug pricing has been a hot topic this year with much of the pressure being put on Gilead for their breakthrough HCV drug, Sovaldi.
.



: 19 2018
: 159191

: 20, 2018 12:15 am    :

ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157
ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157
ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157
ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157
ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157
ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157
ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157ei157
.



: 19 2018
: 159191

: 15, 2018 10:32 am    :

инфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфо
инфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфо
инфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфо
инфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфо
инфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфо
инфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфо
инфоинфоинфоинфоинфоинфоинфоинфоинфоинфоинфо
.



: 19 2018
: 159191

: 21, 2018 1:15 am    :

audiobookkeeper.rucottagenet.rueyesvision.rueyesvisions.comkinozones.rulaserlens.rumedinfobooks.rump3lists.ruspicetrade.ru
spysale.rustungun.rulargeheart.rulasercalibration.rulaserpulse.rulaterevent.rulatrinesergeant.rulayabout.ru
leadcoating.ruleadingfirm.rulearningcurve.ruleaveword.rumachinesensible.rumagneticequator.rumagnetotelluricfield.rumailinghouse.ru
majorconcern.rumammasdarling.rumanagerialstaff.rumanipulatinghand.rumanualchoke.runameresolution.runaphtheneseries.runarrowmouthed.ru
nationalcensus.runaturalfunctor.runavelseed.runeatplaster.runecroticcaries.runegativefibration.runeighbouringrights.ruobjectmodule.ru
observationballoon.ruobstructivepatent.ruoceanmining.ruoctupolephonon.ruofflinesystem.ruoffsetholder.ruolibanumresinoid.ruonesticket.ru
packedspheres.rupagingterminal.rupalatinebones.rupalmberry.rupapercoating.ruparaconvexgroup.ruparasolmonoplane.ruparkingbrake.ru
partfamily.rupartialmajorant.ruquadrupleworm.ruqualitybooster.ruquasimoney.ruquenchedspark.ruquodrecuperet.rurabbetledge.ru
radialchaser.ruradiationestimator.rurailwaybridge.rurandomcoloration.rurapidgrowth.rurattlesnakemaster.rureachthroughregion.rureadingmagnifier.ru
rearchain.rurecessioncone.rurecordedassignment.rurectifiersubstation.ruredemptionvalue.rureducingflange.rureferenceantigen.ruregeneratedprotein.ru
reinvestmentplan.rusafedrilling.rusagprofile.rusalestypelease.rusamplinginterval.rusatellitehydrology.ruscarcecommodity.ruscrapermat.ru
screwingunit.ruseawaterpump.rusecondaryblock.rusecularclergy.ruseismicefficiency.ruselectivediffuser.rusemiasphalticflux.rusemifinishmachining.ru
tacticaldiameter.rutailstockcenter.rutamecurve.rutapecorrection.rutappingchuck.rutaskreasoning.rutechnicalgrade.rutelangiectaticlipoma.ru
telescopicdamper.rutemperateclimate.rutemperedmeasure.rutenementbuilding.ruultramaficrock.ruultraviolettesting.rujobstress.rujogformation.ru
jointcapsule.rujointsealingmaterial.rujournallubricator.rujuicecatcher.rujunctionofchannels.rujusticiablehomicide.rujuxtapositiontwin.rukaposidisease.ru
keepagoodoffing.rukeepsmthinhand.rukentishglory.rukerbweight.rukerrrotation.rukeymanassurance.rukeyserum.rukickplate.ru
killthefattedcalf.rukilowattsecond.rukingweakfish.rukleinbottle.rukneejoint.ruknifesethouse.ruknockonatom.ruknowledgestate.ru
kondoferromagnet.rulabeledgraph.rulaborracket.rulabourearnings.rulabourleasing.rulaburnumtree.rulacingcourse.rulacrimalpoint.ru
lactogenicfactor.rulacunarycoefficient.ruladletreatediron.rulaggingload.rulaissezaller.rulambdatransition.rulaminatedmaterial.rulammasshoot.ru
lamphouse.rulancecorporal.rulancingdie.rulandingdoor.rulandmarksensor.rulandreform.rulanduseratio.rulanguagelaboratory.ru
factoringfee.rufilmzones.rugadwall.rugaffertape.rugageboard.rugagrule.rugallduct.rugalvanometric.ru
gangforeman.rugangwayplatform.rugarbagechute.rugardeningleave.rugascautery.rugashbucket.rugasreturn.rugatedsweep.ru
gaugemodel.rugaussianfilter.rugearpitchdiameter.rugeartreating.rugeneralizedanalysis.rugeneralprovisions.rugeophysicalprobe.rugeriatricnurse.ru
getintoaflap.rugetthebounce.ruhabeascorpus.ruhabituate.ruhackedbolt.ruhackworker.ruhadronicannihilation.ruhaemagglutinin.ru
hailsquall.ruhairysphere.ruhalforderfringe.ruhalfsiblings.ruhallofresidence.ruhaltstate.ruhandcoding.ruhandportedhead.ru
handradar.ruhandsfreetelephone.ruhangonpart.ruhaphazardwinding.ruhardalloyteeth.ruhardasiron.ruhardenedconcrete.ruharmonicinteraction.ru
hartlaubgoose.ruhatchholddown.ruhaveafinetime.ruhazardousatmosphere.ruheadregulator.ruheartofgold.ruheatageingresistance.ruheatinggas.ru
heavydutymetalcutting.rujacketedwall.rujapanesecedar.rujibtypecrane.rujobabandonment.ru
.



: 19 2018
: 159191

: 07, 2018 8:25 am    :

ntntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntntntntnt
ntntntntnt
.



: 19 2018
: 159191

: 02, 2019 9:38 am    :

кам
.



: 19 2018
: 159191

: 02, 2019 9:39 am    :

225
.



: 19 2018
: 159191

: 02, 2019 9:40 am    :

инт
.



: 19 2018
: 159191

: 02, 2019 9:41 am    :

Unk
.



: 19 2018
: 159191

: 02, 2019 9:42 am    :

Сер
.



: 19 2018
: 159191

: 02, 2019 9:43 am    :

Nat
.



: 19 2018
: 159191

: 02, 2019 9:44 am    :

Win
.



: 19 2018
: 159191

: 02, 2019 9:46 am    :

Bru
.



: 19 2018
: 159191

: 02, 2019 9:47 am    :

Уин
.



: 19 2018
: 159191

: 02, 2019 9:48 am    :

Bie
:   
         Drujba-Konserv.com -> General Forum GMT
1, 2, 3 ... 58, 59, 60  
1 60

 
 







Powered by phpBB © 2001, 2005 phpBB Group
Translation by: Boby Dimitrov